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Academic Article Growth factor receptor expression varies among high-grade gliomas and normal brain: epidermal growth factor receptor has excellent properties for interstitial fusion protein therapy.
Academic Article Recombinant toxin DAB389EGF is cytotoxic to human pancreatic cancer cells.
Academic Article Diphtheria toxin-epidermal growth factor fusion protein and Pseudomonas exotoxin-interleukin 13 fusion protein exert synergistic toxicity against human glioblastoma multiforme cells.
Academic Article Safety evaluation of DT388IL3, a diphtheria toxin/interleukin 3 fusion protein, in the cynomolgus monkey.
Academic Article Combination fusion protein therapy of refractory brain tumors: demonstration of efficacy in cell culture.
Academic Article Diphtheria toxin fused to variant interleukin-3 provides enhanced binding to the interleukin-3 receptor and more potent leukemia cell cytotoxicity.
Academic Article Toxicology and pharmacokinetics of DT388IL3, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human interleukin 3 (IL3), in cynomolgus monkeys.
Concept Recombinant Fusion Proteins
Academic Article A diphtheria toxin-epidermal growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells.
Academic Article Expression and purification of the recombinant diphtheria fusion toxin DT388IL3 for phase I clinical trials.
Academic Article Interstitial diphtheria toxin-epidermal growth factor fusion protein therapy produces regressions of subcutaneous human glioblastoma multiforme tumors in athymic nude mice.
Academic Article DAB389EGF fusion protein therapy of refractory glioblastoma multiforme.
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  • Recombinant Fusion Proteins